SYMPTOMS




May occur within seconds of exposure, or be delayed 15 to 30 minutes, or an hour or more after exposure
  • Flushing (warmth & redness of skin)
  • Itching (often in the grain/armpit)
  • Hive

Often accompanied by
  • A feeling of impending doom
  • Anxiety
  • Rapid, irregular pulse

Category: 0 comments

REACTION




Milder reactions may be attributed to asthma attack or sudden episode of hives.

More serious, fetal it may cause heart attack.

Common Causes:
Two major group
  • lgE mediated
  • Non-lgE mediated
lgE mediated
  • True anaphylaxis
  • Requires initial sensitizing exposure, the coating of mast cells and basophils by lgE and the explosive release of chemical mediators upon re-exposure.
Non-lgE mediated
  • Similar to true anaphylaxis but do not require lgE immune reaction.
  • Usually caused by the direct stimulation of mast cells and basophils.
  • This reaction can happen, and often does, on initial as well as subsequent exposures since no sensitization required.



Category: 0 comments

HISTORY



100 years ago, two Parisian Scientist perform studies on the toxin produced by the tentacles of a local jellyfish, the Portuguese Man of War.

They tried to vaccinate dogs after isolating the toxin in hope of obtaining protection or prophylaxis against the toxin

However, they found out that a very small doses of toxin resulted in a new dramatic illness that involves breathing difficulties resulting in death within 30 mins.

Hence, both scientists termed "Anaphylaxis" or against protection.

They rightly concluded that the immune system first becomes sensitized to the allergen over several weeks and upon re-exposure to the same allergen may result in severe reaction.
Category: 0 comments

ANAPHYLAXIS

What is Anaphylatic?

Rapidly developing and serious allergic reaction that affects a number of different areas of the body at one time.

Severe anaphylatic reaction can be fetal

Triggered by substances that are injected or ingested and thus, gain access into the blood stream. Examples explosive reaction involving skin,lungs,nose, throat and GI tract.

Category: 0 comments